Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the cure of a number of myeloma. Its synthesis or examine is critical for making sure the purity and protection from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A essential compound inside the synthesis of imatinib, a drug that targets unique different types of most cancers, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is crucial for optimizing the creation system and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast most cancers, and these intermediates are involved in its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast CIS-3-HYDROXY-4-PHENYL-2-AZETIDINONE cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers including ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and little mobile lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved with the synthesis of adamantane derivatives, that have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-four to control blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted 3 gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication applied to deal with form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).